| Dr. Lin Chia-Lung | |
| Amb. François Chihchung WU | Deputy Minister of Foreign Affairs & Chancellor, Institute of Diplomacy and International Affairs (Since August 18, 2024) |
| Chen Ming-chi | Deputy Minister of Foreign Affairs (since February 20, 2025) |
| Remus Li-Kuo Chen | Vice Minister of Foreign Affairs (Since September 5, 2023) |
| Daniel Diann-Wen Tang | Secretary General (since February 23, 2023) |
| Catherine Y. M. Hsu | Director General, Department of International Information Services (since July, 2021) |
| Andy Kang-I Chen | Director General, The Office of Parliamentarian Affairs (since February 2025) |
| Hsiao Kuang-wei | MOFA Spokesperson and Director General, Public Diplomacy Coordination Council (since December 27, 2024) |
| Shih-Ming Yu | Director General, Department of Civil Service Ethics (since July 2024) |
| Eric Jiun-Yaw Huang | Director General, Department of European Affairs (since January 10, 2024) |
| Peter Sha-li Lan | Director General, Department of East Asian and Pacific Affairs (since July 2023) |
| Anthony Chung-Yi Ho | Director-General, Department of West Asian and African Affairs (Since October 2022) |
| Li-Cheng Cheng | Director General, Department of Latin American and Caribbean Affairs (Since February 26, 2023) |
| Liang-Yu Wang | Director General, Department of North American Affairs (Since August 1, 2023) |
| Jason Chien-Chen Lien | Director-General, Department of Treaty and Legal Affairs (Since July 2022) |
| Jonathan C.Y. Sun | Director General, Department of International Organizations (since August 2023) |
| Hsin-Hsin Chen | Director General, Department of Protocol (since September 2024) |
| Jin-ling Chen | Director-General, Department of General Affairs (Since December 2024) |
| Shih-yi Lu | Department of Personnel (since February 2025) |
| Pei-Hua Lee | Director General, Department of Budget, Accounting and Statistics (Since March 2022) |